Taken from "A Statement from Mannatech"
Coppell, TX – May 11, 2005 – This week Mannatech (NASDAQ: MTEX) a global network marketing provider of nutritional products reported its tenth consecutive quarter of volume growth with record first quarter sales up 46% from the prior year and earnings per share which were up 55%. Mannatech’s high quality proprietary glyconutritional products put it at the forefront of the worldwide boom in sales of nutritional supplements in the U.S as well as other markets where the company does business including Australia, Japan, Canada, New Zealand, the U.K. and Korea. Nutritional supplements account for sales of $19 billion in the U.S. and are growing about 7% annually, and 150 million Americans take dietary supplements each year. (Source: Council for Responsible Nutrition)
Mannatech’s incredible success reflects its professional management team and highly experienced Board of Directors.
While it is not unusual for executives and board members of public companies to sell stock from time to time, the proxy statement submitted to the SEC in April 2005 shows that the company’s Board and management continue to beneficially own 42% of the company’s stock. It should be noted that several Board members have made recent investments in the stock of the company.
Investors can find complete information on insider purchases and sales of Mannatech’s stock, litigation, regulatory issues and the background of its executives and board members in the company’s filings with the SEC. The company believes it complies with applicable FDA and FTC regulations governing its business and takes action against sales associates who are found to have violated the company’s policies concerning advertising and marketing of products.
Mannatech has disclosed that it is the subject of pending litigation, although Mannatech strongly denies the allegations and will continue to vigorously defend itself.
Mannatech believes that its products and business model are sound, that its compliance efforts are strong, and that its CEO, management, and Board fully comply with firm codes of ethical conduct. Mannatech intends to continue its focused growth efforts which have resulted in volume increases and outstanding financial results as it prepares to enter new markets in Taiwan, Germany, and Denmark.
Tuesday, May 29, 2007
Monday, May 28, 2007
Take Two AA-Blocking Supplements
What great news!!
I received a booklet in the mail. I was so excited that I read it from front to back and sent away the card inside.
"Win the War Within" by Dr Floyd H. Chilton, Ph.D. - is the next big thing for me.
Sounds incredible! Dr says is will create a media firestorm like nothing you have ever seen.
Why? B ecause is holds the potential for healing and reversing virtually every major disease and chronic condition that you may face in your lifetime. And that includes Heart disease, Atherosclerosis, Arthritis, Alzheimer's disease, Diabetes, Digestive problems, Liver problems, Allergies, and even Cancer and others, the lists goes on.
The Secret, lies with the release of chemical messengers such as prostaglandins and leukotrienes. When your body produces the right amount of these chemical messengers, your immune system works beautifully. But when you produce too much of these chemicals, the inflamation process spreads like wildfire. Dr Chilton says he likes to think of prostaglandins and leukotrienes as the "lighter fluid" your body produces when inflammation goes out of control.
So we've got to halt your body's bad habit of pumping out excess prostaglandins and leukotrienes. As it turns out, that's far easier than we ever imagined. Why? Because we now know that your cells need a special fatty acid called arachidonic acid or AA to creat excess prostalandins and leukotrienes. Without a sufficient supply of AA, your body just doesn't have the "raw material" it needs to flood your system with these inflammation-triggering messengers.
Taken from Prevention - 30 diseases- One solution
Mannatech's research team for essential glyconutrients are on the cutting edge for optimal health and wellbeing.
I received a booklet in the mail. I was so excited that I read it from front to back and sent away the card inside.
"Win the War Within" by Dr Floyd H. Chilton, Ph.D. - is the next big thing for me.
Sounds incredible! Dr says is will create a media firestorm like nothing you have ever seen.
Why? B ecause is holds the potential for healing and reversing virtually every major disease and chronic condition that you may face in your lifetime. And that includes Heart disease, Atherosclerosis, Arthritis, Alzheimer's disease, Diabetes, Digestive problems, Liver problems, Allergies, and even Cancer and others, the lists goes on.
The Secret, lies with the release of chemical messengers such as prostaglandins and leukotrienes. When your body produces the right amount of these chemical messengers, your immune system works beautifully. But when you produce too much of these chemicals, the inflamation process spreads like wildfire. Dr Chilton says he likes to think of prostaglandins and leukotrienes as the "lighter fluid" your body produces when inflammation goes out of control.
So we've got to halt your body's bad habit of pumping out excess prostaglandins and leukotrienes. As it turns out, that's far easier than we ever imagined. Why? Because we now know that your cells need a special fatty acid called arachidonic acid or AA to creat excess prostalandins and leukotrienes. Without a sufficient supply of AA, your body just doesn't have the "raw material" it needs to flood your system with these inflammation-triggering messengers.
Taken from Prevention - 30 diseases- One solution
Mannatech's research team for essential glyconutrients are on the cutting edge for optimal health and wellbeing.
Sunday, May 27, 2007
Psychological Stress and the Our Immune System
A Meta-Analytic Study of 30 Years of Inquiry
Suzanne C. Segerstrom University of Kentucky
Gregory E. Miller University of British Columbia
The present report meta-analyzes more than 300 empirical articles describing a relationship between psychological stress and parameters of the immune system in human participants. Acute stressors (lasting minutes) were associated with potentially adaptive upregulation of some parameters of natural immunity and downregulation of some functions of specific immunity. Brief naturalistic stressors (such as exams) tended to suppress cellular immunity while preserving humoral immunity. Chronic stressors were associated with suppression of both cellular and humoral measures. Effects of event sequences varied according to the kind of event (trauma vs. loss). Subjective reports of stress generally did not associate with immune change. In some cases, physical vulnerability as a function of age or disease also increased vulnerability to immune change during stressors.
Despite nearly a century of research on various aspects of stress, investigators still find it difficult to achieve consensus on a satisfactory definition of this concept. Most of the studies contributing to this review simply define stress as circumstances that most people would find stressful, that is, stressors. We adopted Elliot and Eisdorfer’s (1982) taxonomy to characterize these stressors. This taxonomy has the advantage of distinguishing among stressors on two important dimensions: duration and course (e.g., discrete vs. continuous). The taxonomy includes five categories of stressors.
Acute time-limited stressors involve laboratory challenges such as public speaking or mental arithmetic. Brief naturalistic stressors, such as academic examinations, involve a person confronting a real-life short-term challenge. In stressful event sequences, a focal event, such as the loss of a spouse or a major natural disaster, gives rise to a series of related challenges. Although affected individuals usually do not know exactly when these challenges will subside,
they have a clear sense that at some point in the future they will.
Chronic stressors, unlike the other demands we have described, usually pervade a person’s life, forcing him or her to restructure his or her identity or social roles.
Glyconutrients have an all over beneficial effect for health and wellbeing.
Suzanne C. Segerstrom University of Kentucky
Gregory E. Miller University of British Columbia
The present report meta-analyzes more than 300 empirical articles describing a relationship between psychological stress and parameters of the immune system in human participants. Acute stressors (lasting minutes) were associated with potentially adaptive upregulation of some parameters of natural immunity and downregulation of some functions of specific immunity. Brief naturalistic stressors (such as exams) tended to suppress cellular immunity while preserving humoral immunity. Chronic stressors were associated with suppression of both cellular and humoral measures. Effects of event sequences varied according to the kind of event (trauma vs. loss). Subjective reports of stress generally did not associate with immune change. In some cases, physical vulnerability as a function of age or disease also increased vulnerability to immune change during stressors.
Despite nearly a century of research on various aspects of stress, investigators still find it difficult to achieve consensus on a satisfactory definition of this concept. Most of the studies contributing to this review simply define stress as circumstances that most people would find stressful, that is, stressors. We adopted Elliot and Eisdorfer’s (1982) taxonomy to characterize these stressors. This taxonomy has the advantage of distinguishing among stressors on two important dimensions: duration and course (e.g., discrete vs. continuous). The taxonomy includes five categories of stressors.
Acute time-limited stressors involve laboratory challenges such as public speaking or mental arithmetic. Brief naturalistic stressors, such as academic examinations, involve a person confronting a real-life short-term challenge. In stressful event sequences, a focal event, such as the loss of a spouse or a major natural disaster, gives rise to a series of related challenges. Although affected individuals usually do not know exactly when these challenges will subside,
they have a clear sense that at some point in the future they will.
Chronic stressors, unlike the other demands we have described, usually pervade a person’s life, forcing him or her to restructure his or her identity or social roles.
Glyconutrients have an all over beneficial effect for health and wellbeing.
Sugars - Biologically Relevant!
Title - Sugar Rush
New Scientist Vol 176 issue 2366 - 26/10/2002
Indeed, scientists are saying that glycomics could fuel a revolution in biology to rival that of the human genome. But it's not going to be easy. "If you ask, what is the glycome for a single cell type, it's probably many thousands of times more complex than the genome," says Ajit Varki, director of the Glycobiology Research and Training Center at the University of California, San Diego. "It's going to be a tough business."
Consider the complexity and subtlety of sugars, and it quickly becomes apparent that "tough" is, if anything, an understatement. For a start, the glycome's basic building blocks are far more numerous and varied than the four letters of the DNA alphabet or the score of amino acids that make proteins.
The complex sugar molecules that help make living things tick are all built up from simple sugars, or "monosaccharides" such as glucose, and about 10 others. Two ring-shaped monosaccharide molecules can link together to form a disaccharide, the other main building block of complex sugars. Things are made more complex because there are several different ways for the monosaccharides to link together, which leave the two units angled in different directions.
The problem only gets worse as monosaccharide and disaccharide units link together to form polysaccharides, the chains of sugars which in turn form the giant structures of complex sugars. These massive molecules, which can contain more than 200 units, not only come as long chains, but also as intricately branched structures that decorate the surfaces of cells like a forest of sugary filigree. It's the three-dimensional shape of these sugars that is key to their functions, such as cell recognition. And there's a further complication: different atoms or groups of atoms may be attached to the basic monosaccharide molecules, subtly changing their properties.
All of this adds up to a massive headache for scientists trying to understand the structures and functions of complex sugars. Do the maths and even a mere six-unit sugar of a kind called a glycosaminoglycan has a staggering 12 billion possible versions. Researchers still have no idea how many of all the possibilities are actually exploited by nature, says Ram Sasisekharan, a bioengineer who leads a multidisciplinary team at the Massachusetts Institute of Technology. "We're still scratching the surface in figuring out which sugars are biologically relevant," he notes.
Mannatech's innovative research and product development teams have created glyconutrients beneficial human health.
New Scientist Vol 176 issue 2366 - 26/10/2002
Indeed, scientists are saying that glycomics could fuel a revolution in biology to rival that of the human genome. But it's not going to be easy. "If you ask, what is the glycome for a single cell type, it's probably many thousands of times more complex than the genome," says Ajit Varki, director of the Glycobiology Research and Training Center at the University of California, San Diego. "It's going to be a tough business."
Consider the complexity and subtlety of sugars, and it quickly becomes apparent that "tough" is, if anything, an understatement. For a start, the glycome's basic building blocks are far more numerous and varied than the four letters of the DNA alphabet or the score of amino acids that make proteins.
The complex sugar molecules that help make living things tick are all built up from simple sugars, or "monosaccharides" such as glucose, and about 10 others. Two ring-shaped monosaccharide molecules can link together to form a disaccharide, the other main building block of complex sugars. Things are made more complex because there are several different ways for the monosaccharides to link together, which leave the two units angled in different directions.
The problem only gets worse as monosaccharide and disaccharide units link together to form polysaccharides, the chains of sugars which in turn form the giant structures of complex sugars. These massive molecules, which can contain more than 200 units, not only come as long chains, but also as intricately branched structures that decorate the surfaces of cells like a forest of sugary filigree. It's the three-dimensional shape of these sugars that is key to their functions, such as cell recognition. And there's a further complication: different atoms or groups of atoms may be attached to the basic monosaccharide molecules, subtly changing their properties.
All of this adds up to a massive headache for scientists trying to understand the structures and functions of complex sugars. Do the maths and even a mere six-unit sugar of a kind called a glycosaminoglycan has a staggering 12 billion possible versions. Researchers still have no idea how many of all the possibilities are actually exploited by nature, says Ram Sasisekharan, a bioengineer who leads a multidisciplinary team at the Massachusetts Institute of Technology. "We're still scratching the surface in figuring out which sugars are biologically relevant," he notes.
Mannatech's innovative research and product development teams have created glyconutrients beneficial human health.
Glyconutritionals and Viral Infections
Glyconutritionals: Implications for Recovery from Viral Infections
Charles J. Gauntt, PhD; Bill H. McAnalley, PhD; Reginald McDaniel, MD
Bruce Peschel EDITOR IN CHIEF
Eileen Vennum, RAC
Abstract
Most coxsackieviral infections are subclinical in humans, but among the estimated 10 million people annually infected by these viruses, those with nutrient-deficient diets are at highest
risk for developing diseases. This review discusses several studies that were performed to assess potential benefits of two glyconutrients on coxsackievirus B3 (CVB3)-induced models of
myocarditis or pancreatitis. Nutritional supplementation in the form of Aloe polymannose (AP) significantly increased titers of anti-viral antibodies in mice challenged with a CVB3 strain that
is both cardiovirulent and pancreatovirulent, but this dietary intervention had no effect on the virus-induced myocarditis in mice. In contrast, administration of a glyconutritional complex
(GC), composed of additional sugars required for cellular glycoconjugate synthesis, to mice challenged with the same CVB3 strain did provide significant benefits over a period of 8 months
to most animals in reversing virusinduced pancreatitis. Another study of rat hepatocytes showed that GC could block chemical depletion of free reduced glutathione, a major cellular antioxidant. These studies suggest a role for AP in stimulating the humoral immune system to produce antiviral antibodies and a role for GC in restoring the antioxidant potential of cells. Both glyconutrients may offer improved health to individuals who may or may not be infected by a virus that could subsequently cause disease.
VIRUSES, VIRAL DISEASES, AND THE COXSACKIEVIRUSES
GROUP B3 (CVB3)
Viruses are incredibly efficient parasites that require living cells in which they replicate, or reproduce, in large numbers. During replication, a virus takes command of the host cell and
converts some or all of the cellular metabolic processes, those normally required to maintain the health of the cell, toward synthesis of viral component parts and then assembly of these
components into new infectious virus particles. During the virus takeover of a cell, some to all essential daily cellular growth and repair processes may not be performed, and this virus-induced irreversible damage can lead to a reduction in function or death of the infected host cell. In addition to directly inducing death of the infected cell(s), viruses can also exert a number of other effects .
When a sufficient number of cells become damaged, major organs.
The Official Publication of The Nutrition Science Site.
Published by the Research and Development Department of Mannatech Incorporated, Coppell, Texas, USA. © 2000 All rights reserved.
JANUARY 26, 2001 VOL 2, NO 2
PROVIDING SCIENTIFIC INFORMATION RELATED TO NUTRITIONAL SACCHARIDES AND OTHER DIETARY INGREDIENTS.
TM
The scientific information in this journal is educational and is not to be used as a substitute for a doctor's care or for proven therapy. People whose diets provide insufficient or excessive amounts of required nutrients may develop far more serious consequences from viral infections than people who experience similar viral infections, but maintain healthier diets.
Charles J. Gauntt, PhD; Bill H. McAnalley, PhD; Reginald McDaniel, MD
Bruce Peschel EDITOR IN CHIEF
Eileen Vennum, RAC
Abstract
Most coxsackieviral infections are subclinical in humans, but among the estimated 10 million people annually infected by these viruses, those with nutrient-deficient diets are at highest
risk for developing diseases. This review discusses several studies that were performed to assess potential benefits of two glyconutrients on coxsackievirus B3 (CVB3)-induced models of
myocarditis or pancreatitis. Nutritional supplementation in the form of Aloe polymannose (AP) significantly increased titers of anti-viral antibodies in mice challenged with a CVB3 strain that
is both cardiovirulent and pancreatovirulent, but this dietary intervention had no effect on the virus-induced myocarditis in mice. In contrast, administration of a glyconutritional complex
(GC), composed of additional sugars required for cellular glycoconjugate synthesis, to mice challenged with the same CVB3 strain did provide significant benefits over a period of 8 months
to most animals in reversing virusinduced pancreatitis. Another study of rat hepatocytes showed that GC could block chemical depletion of free reduced glutathione, a major cellular antioxidant. These studies suggest a role for AP in stimulating the humoral immune system to produce antiviral antibodies and a role for GC in restoring the antioxidant potential of cells. Both glyconutrients may offer improved health to individuals who may or may not be infected by a virus that could subsequently cause disease.
VIRUSES, VIRAL DISEASES, AND THE COXSACKIEVIRUSES
GROUP B3 (CVB3)
Viruses are incredibly efficient parasites that require living cells in which they replicate, or reproduce, in large numbers. During replication, a virus takes command of the host cell and
converts some or all of the cellular metabolic processes, those normally required to maintain the health of the cell, toward synthesis of viral component parts and then assembly of these
components into new infectious virus particles. During the virus takeover of a cell, some to all essential daily cellular growth and repair processes may not be performed, and this virus-induced irreversible damage can lead to a reduction in function or death of the infected host cell. In addition to directly inducing death of the infected cell(s), viruses can also exert a number of other effects .
When a sufficient number of cells become damaged, major organs.
The Official Publication of The Nutrition Science Site.
Published by the Research and Development Department of Mannatech Incorporated, Coppell, Texas, USA. © 2000 All rights reserved.
JANUARY 26, 2001 VOL 2, NO 2
PROVIDING SCIENTIFIC INFORMATION RELATED TO NUTRITIONAL SACCHARIDES AND OTHER DIETARY INGREDIENTS.
TM
The scientific information in this journal is educational and is not to be used as a substitute for a doctor's care or for proven therapy. People whose diets provide insufficient or excessive amounts of required nutrients may develop far more serious consequences from viral infections than people who experience similar viral infections, but maintain healthier diets.
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